Cat Upper Respiratory Infection

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Cat Upper Respiratory Infection Feature

Upper respiratory infections are common in cats, especially among cats housed closely together in such environments as animal shelters, breeding catteries, and boarding facilities. Cat upper respiratory infections are also common among ferals living in large groups outdoors (feral cat colonies). 

What Are Cat Upper Respiratory Infections?

Cats can develop infections of either the upper or lower respiratory tract. Feline upper respiratory infections (URI) affect the nasal passages, sinuses, oral cavity, pharynx and larynx (voice box).

Feline lower respiratory infections affect the trachea, bronchi, and lungs. Cats with upper respiratory infections may also experience lower respiratory infections.

View below the diagram of a cat’s upper and lower respiratory tracts, provided by Cornell Feline Health Center. 

What Causes Cat Upper Respiratory Infections?

Upper respiratory infections in cats occur when a contagious virus, bacteria, or fungus enters the cat’s body, causing an infection in one or more regions of the upper respiratory tract.

Cats may contract viral infections or bacterial infections from direct contact with other infected cats, or from contaminated items in the environment like food bowls and water dishes, litter boxes, bedding, and toys. Cats may pick up fungal infections when they go outdoors. Sometimes, a cat that initially has a viral infection may develop a secondary bacterial infection. 

Many different pathogens can cause upper respiratory infections in cats. Some of the most common include: 

Feline herpesvirus (FHV-1)

Almost all cats will be exposed to feline herpesvirus at some point during their lives. Kittens are most at risk for becoming ill. Feline herpesvirus causes upper respiratory infections as well as fever and corneal ulcers (keratitis). Feline herpesvirus type 1 is cited as being responsible for as many as 80% to 90% of all infectious feline upper respiratory diseases. A vaccine is available for feline herpesvirus (part of a combination vaccine that also protects against feline calicivirus and feline panleukopenia virus).

Feline calicivirus (FCV)

This virus is extremely common and highly contagious. Most cats with feline calicivirus experience upper respiratory symptoms, but some go on to develop lower respiratory symptoms, including viral pneumonia. A vaccine is available for feline calcivirus (part of a combination vaccine that also protects against feline herpesvirus and feline panleukopenia virus).

Chlamydophila felis (C. felis)

This bacterium (which was formerly known as Chlamydia psittaci) mainly causes conjunctivitis, which is inflammation of the conjunctiva (mucous membranes found on the eye and eye lid) and eye discharge. Chlamydophila more commonly affects kittens and young cats. A vaccine is available, but it is not commonly recommended. 


Cats exposed to the bacterium Bordetella bronchiseptica may develop upper respiratory infections. A vaccine is available for B. bronchiseptica, however it is a non-core vaccine, which means it’s not recommended for all cats, but might be recommended for cats that are at high risk of contracting the disease. Bordetella infection is uncommon in pet cats. 

Fungal Infections

Although a variety of fungi can cause respiratory infections in cats, the most common culprit is Cryptococcus neoformans. Cats that inhale the spores of this fungus may experience symptoms of both the upper and lower respiratory tract. Other fungi, such as Aspergillus fumigatus, Histoplasma capsulatum and Blastomyces dermatiditis, generally cause lower respiratory symptoms like pneumonia. 

Symptoms of Cat Upper Respiratory Infections

Cat Upper Respiratory Infection Symptoms

The symptoms of a feline upper respiratory infection resemble those of a human cold or flu, including coughing, sneezing, eye inflammation, lethargy, and more.

Cats with upper respiratory infections may have one or more of the following clinical signs: 

  • Coughing
  • Sneezing
  • Nasal congestion
  • Nasal discharge (runny nose; may be clear or cloudy)
  • Eye discharge (clear or cloudy)
  • Conjunctivitis (inflammation or swelling of the mucous membranes of the eyes)
  • Squinting (blepharospasm)
  • Mouth ulcers 
  • Hoarse voice (meow sounds strange)
  • Fever
  • Lethargy (lack of energy, excessive sleeping)
  • Anorexia (loss of appetite)
  • Enlarged lymph nodes

Cats with upper respiratory symptoms may also experience one or more of the following symptoms of lower respiratory tract infection:

  • Coughing
  • Lethargy (lack of energy, excessive sleeping)
  • Anorexia (decreased or no appetite)
  • Fever
  • Cyanosis (blue or gray lips, gums, and mouth)
  • Difficulty breathing (shallow, labored or rapid breathing)

Treatment & Recovery 

Cat upper respiratory infection recovery

The treatment of a cat upper respiratory infection depends on the infection’s origins and symptoms.

Treatment for an upper respiratory infection depends on what caused the infection and what symptoms the cat is experiencing. Depending on how sick the cat is, it might need only medications given at home, or it might require medications and supportive care like fluids and nutritional therapy. In general, URIs in cats may be treated with some of the following:

  • Antibiotics 
  • Corticosteroids 
  • Nonsteroidal anti-inflammatory drugs
  • Antiviral medications
  • Anti-fungal drugs
  • Intravenous or subcutaneous fluids 
  • Nasal decongestants
  • Nutritional support

The cat’s prognosis depends on what caused the upper respiratory infection. In general, cats with mild to moderate URIs respond well to swift veterinary treatment.

Upper respiratory infections in cats can be caused by many different pathogens, so treatment is dependent on what is causing the infection, whether it be a virus, bacterium or fungus. For that reason, it’s important to seek veterinary care if your cat displays any symptoms of a respiratory infection. Do not attempt to treat your cat with home remedies or use any medication without explicit guidance from your veterinarian.

Frequently Asked Questions

What can I give my cat for upper respiratory infection?

If your cat's upper respiratory infection was caused by something contagious, your veterinarian may instruct you to keep your cat separated from other cats until the symptoms are gone. You vet might also tell you to throughly clean and disinfect your cat's living areas, food and water bowls, litter boxes, bedding and other washable items with a diluted bleach solution. 

How long does it take for a cat to get over an upper respiratory infection?

With appropriate and prompt veterinary treatment, viral and bacterial upper respiratory infections generally clear up within days to weeks. Fungal infections may be trickier to treat. In some cases, treatment for fungal infections might last months. In the case of upper respiratory infections cause by feline herpesvirus, the virus remains in the body for the rest of the cat’s life, cats may experience occasional flare-ups of recurrent URIs.

Can an upper respiratory infection kill a cat?

Upper respiratory infections can be mild or serious. Some URIs lead to lower respiratory tract infections, including pneumonia, which can be life threatening. Even without pneumonia, cats can become extremely sick or even die from a URI, especially if the cat is not eating or drinking enough. Never delay seeking veterinary treatment if your cat is exhibiting any signs of a respiratory infection. 

Can feline upper respiratory infection spread to humans?

The most common viruses and bacteria that cause feline upper respiratory infections cannot infect humans, so in general, cats cannot pass respiratory infections to humans. 

Jackie Brown

About Jackie Brown

Jackie Brown is a freelance writer specializing in the pet industry. She writes on all pet and veterinary topics, including general health and care, nutrition, grooming, behavior, training, veterinary and health topics, rescue and animal welfare, lifestyle, and the human-animal bond. Jackie is the former editor of numerous pet magazines and is a regular contributor to pet magazines and websites.

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